Az életminőség és a munkaképesség alakulása fázisprofilaktikus lamotriginkezelés során bipoláris betegekben 6 hónapos, prospektív, obszervációs vizsgálat /
Bipolar disorder is a lifelong illness requiring lifelong pharmacotherapy. Therefore besides symptomatic remission, achievement of full work-related functioning and restoration of quality of life is a priority during successful treatment. The present prospective, observational, non-intervention stud...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2016
|
| Sorozat: | NEUROPSYCHOPHARMACOLOGIA HUNGARICA
18 No. 1 |
| mtmt: | 3055947 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/11137 |
| LEADER | 02621nab a2200229 i 4500 | ||
|---|---|---|---|
| 001 | publ11137 | ||
| 005 | 20191129153328.0 | ||
| 008 | 170407s2016 hu o 0|| zxx d | ||
| 022 | |a 1419-8711 | ||
| 024 | 7 | |a 3055947 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a zxx | ||
| 100 | 1 | |a Gonda Xénia | |
| 245 | 1 | 3 | |a Az életminőség és a munkaképesség alakulása fázisprofilaktikus lamotriginkezelés során bipoláris betegekben |h [elektronikus dokumentum] : |b 6 hónapos, prospektív, obszervációs vizsgálat / |c Gonda Xénia |
| 260 | |c 2016 | ||
| 300 | |a 57-67 | ||
| 490 | 0 | |a NEUROPSYCHOPHARMACOLOGIA HUNGARICA |v 18 No. 1 | |
| 520 | 3 | |a Bipolar disorder is a lifelong illness requiring lifelong pharmacotherapy. Therefore besides symptomatic remission, achievement of full work-related functioning and restoration of quality of life is a priority during successful treatment. The present prospective, observational, non-intervention study focused on investigating the effect of lamotrigine therapy on the quality of life and work-related function of bipolar patients in outpatient care. METHODS: 969 bipolar or schizoaffective outpatients participated in the study who previously did not receive lamotrigine therapy. Our present phase-prophylactic study was a prospective, observational, non-intervention study with a six-month follow-up. Evaluations took place at baseline and at months 1, 2, 3 and 6. Patients were followed with a Clinical Global Impression-Severity (CGI-S) and Clinical Global Impression-Improvement (CGI-I). Changes in work-related function was evaluated using Social Adjustment Scale (SAS), while quality of life was assessed with the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) scale. RESULTS: SAS scoreds showed a consistent decrease in the overall sample and in all CGI-S initial groups reflecting the improvement of work-related function during the six months of the follow-up. Q-LES-Q values in the whole sample and in all initial CGI-S groups showed a steady increase indicating a continuous increase in quality of life during the study. CONCLUSION: Our results indicate that during long-term prophylactic lamotrigine therapy the work function and quality of life of bipolar patients shows a significant improvement, therefore lamotrigine provides a possibility for full functional remission and restoration of quality of life. | |
| 700 | 0 | 1 | |a Kálmán János |e aut |
| 700 | 0 | 1 | |a Döme Péter |e aut |
| 700 | 0 | 1 | |a Rihmer Zoltán |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/11137/1/Az_eletminoseg_es_a_munkakepesseg_alakulasa_u.pdf |z Dokumentum-elérés |