Evaluation of bloodstream infections during chemotherapy-induced febrile neutropenia in patients with malignant hematological diseases single center experience /

From year to year, it is important to get an overview of the occurrence of causative agents in febrile neutropenic patients to determine the empiric treatment. Thus our aims were to evaluate a four-year period regarding the prevalence of bloodstream infections and the most important causative agents...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Piukovics Klára
Terhes Gabriella
Lázár Andrea
Tímár Flóra
Borbényi Zita
Zsoldiné Urbán Edit
Dokumentumtípus: Cikk
Megjelent: Akadémiai Kiadó 2015
Sorozat:EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY 5 No. 3
doi:10.1556/1886.2015.00021

mtmt:2961054
Online Access:http://publicatio.bibl.u-szeged.hu/12080
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520 3 |a From year to year, it is important to get an overview of the occurrence of causative agents in febrile neutropenic patients to determine the empiric treatment. Thus our aims were to evaluate a four-year period regarding the prevalence of bloodstream infections and the most important causative agents. During this period, 1,361 patients were treated in our hematology ward because of various hematological disorders. 812 febrile episodes were recorded in 469 patients. At that time, 3,714 blood culture (BC) bottles were sent for microbiological investigations, 759 of them gave positive signal. From the majority of positive blood culture bottles (67.1%), Gram-positive bacteria, mainly coagulase-negative staphylococci (CNS), were grown. Gram-negative bacteria were isolated from 32.9% of the positive blood culture bottles, in these cases the leading pathogen was Escherichia coli. The high prevalence of CNS was attributed to mainly contamination, while lower positivity rate for Gram-negative bacteria was associated with the use of broad-spectrum empiric antibiotic treatment. 
700 0 1 |a Terhes Gabriella  |e aut 
700 0 1 |a Lázár Andrea  |e aut 
700 0 1 |a Tímár Flóra  |e aut 
700 0 1 |a Borbényi Zita  |e aut 
700 0 2 |a Zsoldiné Urbán Edit  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/12080/1/eujmi_05_199_u.pdf  |z Dokumentum-elérés