The role of stereoselectivity of chemosensitizers in the reversal of multidrug resistance of mouse lymphoma cells
The effect of three different stereoisomer pairs of CNS (central nervous system) active compounds was studied on the activity of human mdr1 p-glycoprotein. The methotrimeprazine, clopenthixol and butaclamol isomers had an antiproliferative effect (ID50) on the mdr1 expressing cells at 0.250 microgra...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
1998
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| Sorozat: | ANTICANCER RESEARCH
18 No. 4C |
| Tárgyszavak: | |
| mtmt: | 1857806 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/31578 |