Statistical analysis methods in explaining the relationship between the bioconcentration factor and molecular descriptors - applications to small polycyclic aromatic hydrocarbons

The investigation of the chemical properties and potential environmental behavior of toxic compounds represents a subject of significant interest for researchers, as it allows them to develop strategies for protecting both human health and the integrity of the natural environment. In the present stu...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Tudoran Marina Alexandra
Taranu Ioan
Taranu Bogdan-Ovidiu
Testületi szerző: 31th International Symposium on Analytical and Environmental Problems
Dokumentumtípus: Könyv része
Megjelent: University of Szeged Szeged 2025
Sorozat:Proceedings of the International Symposium on Analytical and Environmental Problems 31
Kulcsszavak:Környezetkémia
Tárgyszavak:
Online Access:http://acta.bibl.u-szeged.hu/88686
Leíró adatok
Tartalmi kivonat:The investigation of the chemical properties and potential environmental behavior of toxic compounds represents a subject of significant interest for researchers, as it allows them to develop strategies for protecting both human health and the integrity of the natural environment. In the present study, computational and statistical methods are employed to explore the relationship between the bioconcentration factor and surface area, polarizability, hydration energy, HOMO and LUMO energies, and the HOMO-LUMO gap, in a set of polycyclic aromatic hydrocarbon (PAH) molecules. This approach can be used as an alternative to existing QSAR methods to facilitate the assessment of bioaccumulation factors for a wider range of molecules, thereby extending the applicability of these existing procedures.
Terjedelem/Fizikai jellemzők:255-259
ISBN:978-963-688-078-1