A green, isocyanide-based three-component reaction approach for the synthesis of multisubstituted ureas and thioureas
A one-pot, isocyanide based multicomponent protocol was presented starting from secondary amines towards (thio)urea derivatives and utilized for the construction of a diverse 27-membered chemical library. Following a green compatible microwave assisted condition, the formed N,N′-multisubstituted (th...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
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2018
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| Sorozat: | TETRAHEDRON LETTERS
59 No. 1 |
| doi: | 10.1016/j.tetlet.2017.11.053 |
| mtmt: | 3339611 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/14530 |
| Tartalmi kivonat: | A one-pot, isocyanide based multicomponent protocol was presented starting from secondary amines towards (thio)urea derivatives and utilized for the construction of a diverse 27-membered chemical library. Following a green compatible microwave assisted condition, the formed N,N′-multisubstituted (thio)ureas were obtained in up to 85% yield. © 2017 Elsevier Ltd |
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| Terjedelem/Fizikai jellemzők: | 54-57 |
| ISSN: | 0040-4039 |