Intraocular penetration of tri tetracyclines after parenteral and subconjunctival administration

Methacycline, doxycycline, and oxytetracycline were administered to rabbits in the form of tritetracycline complexes and pyrrolidinomethyloxytetracycline by i.v. or subconjunctival injection. Antibiotic levels in the aqueous humor proved to be highest after trimethacycline when the substances were a...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kahán Ilona L
Pápai Ibolya
Hammer Helga
Dokumentumtípus: Cikk
Megjelent: 1974
Sorozat:ALBRECHT VON GRAEFES ARCHIV FUR KLINISCHE UND EXPERIMENTELLE OPHTHALMOLOGIE 190 No. 3
Tárgyszavak:
doi:10.1007/BF00407099

mtmt:1273914
Online Access:http://publicatio.bibl.u-szeged.hu/33916
Leíró adatok
Tartalmi kivonat:Methacycline, doxycycline, and oxytetracycline were administered to rabbits in the form of tritetracycline complexes and pyrrolidinomethyloxytetracycline by i.v. or subconjunctival injection. Antibiotic levels in the aqueous humor proved to be highest after trimethacycline when the substances were administered by the i.v. route and after administration of tridoxycycline when they were given subconjunctivally. Administration of trioxytetracyclines resulted in higher aqueous humor levels than pyrrolidinomethyloxytetracycline after both i.v. and subconjunctival administration. Chemosis was never observed.
Terjedelem/Fizikai jellemzők:257-265
ISSN:0065-6100