Intraocular penetration of tri tetracyclines after parenteral and subconjunctival administration
Methacycline, doxycycline, and oxytetracycline were administered to rabbits in the form of tritetracycline complexes and pyrrolidinomethyloxytetracycline by i.v. or subconjunctival injection. Antibiotic levels in the aqueous humor proved to be highest after trimethacycline when the substances were a...
Elmentve itt :
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Dokumentumtípus: | Cikk |
Megjelent: |
1974
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Sorozat: | ALBRECHT VON GRAEFES ARCHIV FUR KLINISCHE UND EXPERIMENTELLE OPHTHALMOLOGIE
190 No. 3 |
Tárgyszavak: | |
doi: | 10.1007/BF00407099 |
mtmt: | 1273914 |
Online Access: | http://publicatio.bibl.u-szeged.hu/33916 |
Tartalmi kivonat: | Methacycline, doxycycline, and oxytetracycline were administered to rabbits in the form of tritetracycline complexes and pyrrolidinomethyloxytetracycline by i.v. or subconjunctival injection. Antibiotic levels in the aqueous humor proved to be highest after trimethacycline when the substances were administered by the i.v. route and after administration of tridoxycycline when they were given subconjunctivally. Administration of trioxytetracyclines resulted in higher aqueous humor levels than pyrrolidinomethyloxytetracycline after both i.v. and subconjunctival administration. Chemosis was never observed. |
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Terjedelem/Fizikai jellemzők: | 257-265 |
ISSN: | 0065-6100 |